Can fMRI Read Your Mind? (BS 156 with Russ Poldrack)
/BS 156 is an interview with Stanford psychologist Russell Poldrack, author of The New Mind Readers: What Neuroimaging Can and Cannot Reveal about Our Thoughts.
Read MoreA Podcast that Explores how neuroscience is unraveling the mystery of how our brain makes us human
Brain Science is a monthly podcast Brain Science, hosted by Ginger Campbell, MD. We explore how recent discoveries in neuroscience are helping unravel the mystery of how our brain makes us human. The content is accessible to people of all backgrounds.
BS 156 is an interview with Stanford psychologist Russell Poldrack, author of The New Mind Readers: What Neuroimaging Can and Cannot Reveal about Our Thoughts.
Read MoreBS 144 is an interview with Dr. Angela Friederici, author of Language in Our Brain: The Origins of a Uniquely Human Capacity. This is an extensive review of several decades of research, but this interview makes the field accessible to listeners of all backgrounds.
Read MoreDr. William Uttal, who died last month at the age of 86, had a very unusual career, going from physics and engineering to psychology and cognitive science. I think his unique background contributed to the refreshing skepticism that he brought to the growing use of imaging (especially fMRI) in the cognitive sciences.
He was a prolific writer on the subject and back in 2012 I had the honor of talking with him about his book Mind and Brain: A Critical Appraisal of Cognitive Neuroscience. In addition to shedding light on the limitations of imaging (such as poor reproducibility), Dr. Uttal also argued that it was premature to abandon other psychological testing methods.
This month I am replaying that 2012 interview. Brain Science 132 includes a new introduction and closing remarks. While Dr. Uttal's writing was aimed at a technical audience I think it is important for listeners of all backgrounds to be aware of these issues because they remain as relevant as ever.
FREE: audio mp3 (click to stream, right click to download)
Episode Transcript [Buy for $2]
Premium Subscribers have unlimited access to ALL old episodes and transcripts.
New episodes of the Brain Science Podcast are ALWAYS FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links to the audio files.
Uttal, W. R. (2011) Mind and Brain: A Critical Appraisal of Cognitive Neuroscience.
Uttal, W. R. (2009) Neuroscience in the Courtroom: What Every Lawyer Should Know About the Mind and the Brain.
Ihnen, S. K. Z., Church, J. A.. Petersen, S. E., & Schlaggar, B.L. (2009) Lack of generalizability of sex difference in the fMRI Bold Activity associated with language processes in adults. NeuroImage, 45, 1020-1032.
Ioannidis, J. P. A. (2005). "Why Most Published Research Findings Are False". PLoS Medicine 2 (8): e124.
BSP 46: How fMRI works.
You can now record your voice feedback at http://speakpipe.com/docartemis.
Brain Science is now 100% listener supported. You can support the show via direction donations, Premium Subscription, or Patreon.
I am planning to attend this year's Society of Neuroscience Meeting, which is being held in Washington DC November 11-15, 2017. Please email at brainsciencepodcast@gmail.com if you are going to be in Washington during those dates. If there is enough interest I will arrange a listener meet-up.
I am also in the early stages of planning a trip to Australia in 2018 and would love to hear from Australian listeners for ideas and advice, including leads on speaking opportunities.
The Human Connectome is a description of the structural connectivity of the human brain, but according to Olaf Sporns, author of Discovering the Human Connectome, this description must include a description of the brain's dynamic behavior. I first talked with Sporns back in BSP 74, but BSP 103 gave us a chance to talk about recent progress in connectomics.
Sporns sees the study of the brain's connections as fundamental to understanding how the brain works.
"It will allow us to ask new questions that perhaps we couldn’t ask before. It will be a foundational data set for us, just like the genome is. We will not be able to imagine neuroscience going back to a time when we did not have the connectome, but it will not give us all the answers.”
In his first book, Networks of the Brain, Sporns described how Network Theory provides important tools for dealing with the large data sets that are created by studying complex systems like the human brain. In BSP 103 we discuss both the challenges and the promise of Discovering the Human Connectome.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. The 50 most recent episodes are also free. Just subscribe in your favorite podcasting app.
The Autistic Brain: Thinking Across the Spectrum by Temple Grandin (with Richard Panek), is a tremendous gift, not just to patients and their families, but also to teachers, mentors, friends, and everyone who is interested in understanding how our brains make us who we are.
I think that this is a book everyone should read because as we come to appreciate the fact that the strengths and challenges of autism occur across a broad spectrum, we may also realize that some of these issues actually affect people who aren't considered autistic. It is not the label that matters. What does matter is recognizing that each of us has his or her own strengths and weaknesses, but thanks to brain plasticity, we all have the potential to nurture our strengths and, when necessary, accommodate our weaknesses.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
The Autistic Brain: Thinking Across the Spectrum by Temple Grandin, with Richard Panek; Also available from Audible.com.
Paul Offit, MD reviews the evidence that autism is NOT caused by vaccines
Please see the episode transcript for additional links and references.
I am still trying to schedule an interview with Dr. Temple Grandin, but there is a possibility that the next episode of the Brain Science Podcast will not come out until August 2013.
The Deadline for listener submissions to Episode 100 is August 1, 2013.
Several products are not available directly on this website including the PDF version of Are You Sure? The Unconscious Origins of Certainty by Ginger Campbell, MD and a zip file contain BSP 1-10. Click here to learn more.
Be sure to sign up for the Brain Science Podcast Newsletter so that you can receive show notes automatically and NEVER miss a new episode. (But there was a glitch last month, so if you did not get the show notes for BSP 97, please click here.
William Uttal, PhD
There is nothing more exciting than the mind/brain problem" according to Dr. William Uttal, author of Mind and Brain: A Critical Appraisal of Cognitive Neuroscience. In the latest episode of the Brain Science Podcast (BSP 83) I talked with Dr. Uttal about why he feels that brain imaging can not solve this mystery.
First, there is the problem that brain imaging represents the wrong level of analysis because every spot you see on a brain scan actaully represents thousands of neurons. This means that the activity and interaction between individual neurons has been lost. Then there is the problem of reproducibility, with divergent results between studies.
The evidence is accumulating that "much of the brain responds to any stimulus, and every area of the brain participates in multiple functions." This means that asking where a given function occurs may be the wrong question.
BSP 83 represents an on-going discussion of these issues, so I have included links to related episodes in the show notes.
Related Podcasts:
Send me feedback at gincampbell at mac dot.com.
In his latest book, Who's in Charge?: Free Will and the Science of the Brain, respected neuroscientist, Michael S. Gazzaniga, explores how the discoveries of neuroscience impact how we see ourselves as human beings. After providing a brief review of 20th century neuroscience, and even some of the work from the past decade, Dr. Gazzaniga concludes that nothing neuroscience has discovered changes the fact that "we are personally responsible agents and are to be held accountable for our actions."
Gazzaniga's position contrasts with those who think that recent discoveries show that the brain creates the mind in solely "upwardly causal" way, and who argue that since much of what our brain does is outside our conscious awareness or control, we should not be held responsible for our actions. Who's in Charge?: Free Will and the Science of the Brain presents what I think is a convincing argument against this common position.
In the latest episode of the Brain Science Podcast (BSP 82) I present a detailed discussion of Dr. Gazzaniga's book.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
Who's in Charge?: Free Will and the Science of the Brain, by Michael S. Gazzaniga.
The Ethical Brain: The Science of Our Moral Dilemmas, by Michael S. Gazzaniga.
A Different Universe: Reinventing Physics from the Bottom Down, by Robert B. Laughlin (2006).
Incomplete Nature: How Mind Emerged from Matter, by Terrence W. Deacon.
Anderson, P. W., (1972). "More is different." Science, 177(20470, 393-396.
See the free episode transcript for additional references.
Links to episodes of the Brain Science Podcast that are mentioned in BSP 82.
BSP 81: Interview with Patricia Churchland about the brain and morality.
BSP 53: Discussion of Did My Neurons Make Me Do It?: Philosophical and Neurobiological Perspectives on Moral Responsibility and Free Will by Nancey Murphy, Warren S. Brown. (Also BSP 62)
BSP 35: Discussion of Mirror Neurons.
BSP 66: For more on scrub jays.
BSP 3: Memory and the use of animal models.
BSP 38: Interview with Jeff Hawkins.
BSP 47: Brain Evolution.
BSP 74: "Small world architecture" in brain networks (Olaf Sporns).
BSP 75: Interview with David Eagleman (arguments for legal reform).
BSP 76: "Choking" with Dr. Sian Beilock.
BSP 56: Interview with Eve Marder (implications of muliple realizability in neuronal circuits).
Post comments on the BSP Facebook Fan Page or on the BSP Google+ page.
Join the BSP Group at Goodreads.com.
Don't forget to sign up for the Brain Science Podcast Newsletter.
Next month's episode will be an interview with Bill Uttal, author of Mind and Brain: A Critical Appraisal of Cognitive Neuroscience
This podcast is supported by listener donations. Thank you!
Send feedback to brainsciencepodcast@gmail.com.
Networks of the Brain by Olaf Sporns is an excellent comprehensive introduction to the use of Network Theory to study both the brain and the nervous systems of invertebrates.
In Episode 74 of the Brain Science Podcast, I interviewed Dr. Sporns (Indiana University) about some of the key ideas in his book. Network Theory is becoming increasingly important as a tool for dealing with the massive amounts of data being generated by current techniques, such as brain imaging. It is also a valuable tool for dealing with the fact that nervous systems consist of multiple scales (from the molecular level up to billions of neurons), which can not be reduced to a single scale.
While Networks of the Brain will be of greatest interest to those working in neuroscience and to those with a background in fields like engineering, mathematics, and computer science, this interview provides an introduction for listeners of all backgrounds.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
Olaf Sporns, PhD (Indiana University): website, email: osporns at indiana.edu.
Networks of the Brain, by Olaf Sporns (MIT Press, 2011).
Rhythms of the Brain, by György Buzsáki.
Watts, DJ, Strogatz SH. "Collective Dynamics of 'small-world' networks." Nature 393: 440-442 (1998).
Fodor, JA. The Modularity of the Mind. (1983).
BSP 31: Interview with György Buzsáki, author of Rhythms of the Brain.
BSP 46: Discussion of Brain Imaging, including Diffusion Imaging.
BSP 56: Interview with Dr. Eve Marder about the use of circuit theory in neuroscience.
BSP 61: Mapping the Brain (and generating huge amounts of data).
The Brain Science Podcast will be returning to a monthly schedule on July 1, 2011.
Please join the new Brain Science Podcast Discussion Forum at GoodReads.com.
Dr. Campbell gave a talk in London last month entitled "Why Neuroscience Matters." (Available here.)
Dr. Campbell will be a speaker at The Amazing Meeting 9, July 14-17,2011 in Las Vegas, NV.
Don't forget to check out the Books and Ideas podcast and SCIENCEPODCASTERS.ORG.
The Brain Science Podcast app is available for iPhone, Android, and iPad. If you have purchased the iPhone version, it will now work on your iPad (no additional purchase needed). The iPad is the perfect device for reading episode transcripts, especially if you want to read along as you listen.
Send Dr. Campbell email at brainsciencepodcast@gmail.com.
Episode 57 of the Brain Science Podcast is an interview with neuropsychologist, Dr. Chris Frith, author of Making up the Mind: How the Brain Creates Our Mental World. Our brain processes information about the world outside us (via our senses) in the same way that it processes information from within our bodies and from our own mental world. In this interview. Dr. Frith and I explore the implications from recent discoveries about how our brain generates our mental world.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
Chris Frith, PhD: University College London Wellcome Trust Center for Neuroimaging.
Necker cube: a visual illusion that shows that some visual processing can not be changed by top-down feedback.
PubMed: a public service of the US National Library of Medicine and the National Institutes of Health.
Bayes, T (1763). “An essay toward solving a problem in the doctrine of chance.” Philosophical Transactions of the Royal Society of London, 53, 470-418.
Blakemore, SJ, Wolpert DM, and Frith, CD (1990) Central Cancellation of self produced tickle sensation. Nature Neuroscience, 1(7), 635-640.
Botvinick, M and Cohen, J (1998) Rubber hands "feel" touch that the eyes see. Nature, 391(6669), 756.
Kilner, JM, Paulignan, Y, and Blakemore, SJ, (2003) An interference effect of observed biological movement on action.Current Biology, 13(6), 522-525.
Rizzolatti, G and Craighero, L (2004). The mirror-neuron system. Annual Review of Neuroscience, 27, 169-192.
Wicker, B, Keysers, C, Plaily,J, Royet, JP, Galese, V, and Rizzolatti, G (2003). Both of us disgusted in My insula: The common neural basis of seeing and feeling disgust.Neuron. 40(3), 655-664.
Wegner, D (2003). The Illusion of Conscious Will, MIT Press.
Wegner, DM, Fuller, VA and Sparrow, B. (2003) Clever hands: Uncontrolled intelligence in facilitated communication. Journal of Personal Social Psychology, 85(1), 5-19.
*These references are from Making up the Mind: How the Brain Creates Our Mental World by Chris Frith.
Send feedback to brainsciencepodcast@gmail.com.
Dr. Campbell at Dragon*Con 2008
Brain Science Podcast #46 is a discussion of brain imaging with Dr. Shella Keilholz and Dr. Jason Schneiderman. The focus of our discussion is functional magnetic resonance imaging (fMRI), which is revolutionizing neuroscience. We talked about both the strengths and weaknesses of this technique. Both of my guests agree that mainstream coverage of this technique tends to exaggerate what we can actually tell from this kind of brain scan. An important principle is that the scan of any single individual can vary greatly from day to day, which means that valid conclusions require data from a large number of people.
Since this episode was recorded LIVE in the Podcasting Track at Dragon*Con 2008, it includes audience questions at the end, which helped bring out additional ideas. I have posted an edited version (but there is still some noise from the room next door). If you are interested in hearing the raw unedited version, click here. I also want to thank Swoopy from Skepticality for all the work she did to make the podcasting track a great success.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
Shella Keilholz, PhD, is an assistant professor of Biomedical Engineeering at Georgia Tech and the Emory School of Medicine in Atlanta, GA. She is doing studies that involve correlating fMRI scans with the reading from electrodes placed in rat brains. This work is fundamental to improving the correlation between fMRI scans, which reflect brain activity only indirectly, and what is actually happening in the neurons of the brain.
Jason Schneiderman, PhD studied psychology before earning his PhD in neuroscience. His dissertation involved the use of diffusion tensor imaging, which is a new method of scanning that is being used to track the axonal connections in the brain. He is currently doing a post-doctoral fellowship at Harvard Medical School, where his team is trying to determine if the connections in the brains of young schizophrenics are different from normal. The goal is to improve early diagnosis because early intervention makes a big difference.
Must Read Paper on fMRI -and- The Worst fMRI Science Journalism Ever (Pure Pedantry, 6/27/08)
What we can do and what we cannot do with fMRI by Nikos K. Logothetis, Nature 453, 869-878 (12 June 2008). Note: full text is only available to subscribers.
Can fMRI tell if I secretly love the Yankees? - The Great Beyond (Nature.com) June 16, 2008.
Donations and Subscriptions are appreciated.
Send email feedback to Ginger Campbell, MD at brainsciencepodcast@gmail.com.
Episode #15 of the Brain Science Podcast is an interview with Dr. Read Montague of the Baylor School of Medicine. We discuss his recent book, Why Choose this Book? How we Make Decisions (2006).
Premium Subscribers now have unlimited access to all old episodes and transcripts.
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
What is computational neuroscience?
What is the computational theory of the mind (CTOM)?
How isthe objection that the CTOM doesn't account for meaning answered ?
What about choice and responsibility?
Is there room for free will in this model?
This episode is a discussion of The Future of the Brain: The Promise and Perils of Tomorrow's Neuroscience, by British neuroscientist, Steven Rose. Unlike most episodes of the Brain Science Podcast, the emphasis of this episode is on asking what kind of ethical dilemmas might be posed by our increased knowledge of how the brain works.
Why the mind is more than the brain.
Why the mind is more than genetics and biochemistry.
How we still have a long way to go before we can fully understand how the brain-body generates the mind.
Problems and dangers of reductionism.
Implications for freedom and personal responsibility.
Examples from the history of science that demonstrate why these concerns are valid.
The "Paradox of Memory."
Some email from listeners.
One issue I only mention briefly on the podcast is Rose's attack on evolutionary psychology. If you are interested in learning more about this, you might want to read the transcript of a debate between Steven Rose and Stephen Pinker, which was held in 1998. It is on the Edge website, which is an interesting website even though it lacks an RSS feed.
Premium Subscribers now have unlimited access to all old episodes and transcripts.
Buy BSP 1-10 (zip file of mp3 files)
New episodes of the Brain Science Podcast are always FREE. All episodes posted after January 1, 2013, are free. See the individual show notes for links the audio files.
Any amount is appreciated.
Pledge $4/month or more with Patreon and get all new episode transcripts.
Supporters who pledge $10+ per month also get ad-free versions of each new episode.
Copyright 2013 - 2023 | Virginia Campbell, MD. All Rights Reserved.